Research

Laboratory of Neurobiology for Translational Medicine

Il Neurobiology Laboratory for Translational Medicine supports the clinic from a point of view biochemical, genetic and molecular, collecting as much data as possible from the same patient in order to better characterize him by adding the molecular aspect to the clinical picture.

The laboratory is equipped for biochemical analysis (western blot, immunoprecipitation, protein expression, bioinformatics), immunohistochemistry (fluorescence) and collaborates closely with research groups with which he carries out mass spectrometry and genetic analysis (rtPCR, PCR, Sequencing).

Activities

The main activity concerns the analysis of human samples coming from blood samples of patients affected by central nervous system (CNS) diseases including Ischemia, Amyotrophic Lateral Sclerosis (ALS), Alzheimer's e Parkinson's, on which the investigations are being carried out molecular, genetic and proteomic mechanisms which can vary both during the onset and development of the pathologies.

The laboratory is mainly focused onidentification of new diagnostic and prognostic biomarkers with neurological pathologies, and in addition it is studied as a rehabilitation process can create biomolecular modifications through the search for potential rehabilitation biomarkers.

In the light of what is today called “personalized medicine”, our goal is to be able to identify abiological footprint of CNS pathologies that helps improve the diagnosis, Research pharmacological and also the rehabilitation.

for experimental analyses they are mainly used biological samples from Internal institutional biobank, which allows us to compare the experimentally obtained results with those clinical noted during the collection of the biological sample.